New research paves way for tools to target superbug

A. baumannii is a WHO-recognized critical priority pathogen for research, due to antibiotic resistance

By Greg Basky

A scanning electron micrograph of a cluster of Acinetobacter baumannii bacteria. Source: CDC's Public Health Image Library Image #6498 Photo Credit: Janice Carr

The work presented in this video describes a collaborative project regarding the bacterial pathogen Acinetobacter baumanii lead by Tom Bateman in the Moraes Lab. Structural, biochemical and in vitro growth assays were performed by members of the Moraes Lab with help from staff at the Canadian Light Source staff for data collection using the CMCF beamlines. Animal work was performed in collaboration with members of Scott Gray-Owen's Lab at the University of Toronto and Wangxue Chen’s Lab at the National Research Council in Ottawa.

Bateman, T.J., Shah, M., Ho, T.P. et al. A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nat Commun 12, 6270 (2021). https://doi.org/10.1038/s41467-021-26545-9

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